This is going to be completely subjective. I'm going to post a quote from WSPA-3 from this last weekend. The first person who can explain just what she was talking about, and the person who comes up with the funniest (IMNSHO) interpretation will both win a copy of this CD.
So, she said
"Why is there bread in your sandwich?"
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edit The actual reason has been guessed, but funniness can still win you one of these.